短暂性全面性遗忘症与偏头痛的关联。

The transient global amnesia-migraine connection.

作者信息

Crowell G F, Stump D A, Biller J, McHenry L C, Toole J F

出版信息

Arch Neurol. 1984 Jan;41(1):75-9. doi: 10.1001/archneur.1984.04050130081029.

DOI:10.1001/archneur.1984.04050130081029

Abstract

Twelve patients with transient global amnesia (TGA) were studied. Seven (58%) of the 12 had a headache during their attack; five (42%) of the 12 were migraineurs. Measurement of regional cerebral blood flow (rCBF) by the xenon Xe 133 inhalation method showed similar patterns of flow in five of the seven patients tested. The rCBF abnormalities were impaired vasomotor response in the watershed area between the middle cerebral artery and posterior cerebral artery territories, and/or focal ischemia in the inferior part of the temporal lobe. These rCBF abnormalities differed from those seen in patients with carotid transient ischemic attacks (TIAs) and vertebrobasilar TIAs. We speculate that the vasomotor phenomena in migraine may play a major role in the cause of TGA.

摘要

对12例短暂性全面性遗忘症（TGA）患者进行了研究。12例中有7例（58%）在发作期间出现头痛；12例中有5例（42%）为偏头痛患者。采用氙Xe 133吸入法测量局部脑血流量（rCBF），结果显示，在接受测试的7例患者中，有5例的血流模式相似。rCBF异常表现为大脑中动脉和大脑后动脉供血区域之间分水岭区的血管舒缩反应受损，和/或颞叶下部的局灶性缺血。这些rCBF异常与颈动脉短暂性脑缺血发作（TIA）和椎基底动脉TIA患者中所见的异常不同。我们推测，偏头痛中的血管舒缩现象可能在TGA的病因中起主要作用。