Albers H E, Moline M L, Moore-Ede M C
J Endocrinol. 1984 Jan;100(1):101-5. doi: 10.1677/joe.0.1000101.
Sex differences in the hourly values of serum LH were examined in male and female Syrian hamsters exposed to either long photoperiods (14 h light: 10 darkness; 14L: 10D) or short photoperiods (6L: 18D). In long photoperiods, females exhibited a pro-oestrous surge of LH in response to high levels of circulating oestradiol (1047.36 +/- 90.68 pmol/l), while LH values in male hamsters remained essentially constant. In females housed in short photoperiods oestradiol levels were reduced by fivefold; however, a discrete surge in serum LH, similar to that seen at pro-oestrus in females exposed to long photoperiods, was observed. Although exposure to a short photoperiod eliminates the requirement of a positive feedback of oestrogen for the expression of an afternoon surge in LH, male hamsters housed in short photoperiods showed no indication of an afternoon surge in serum LH. These observations indicate that sex differences in the neural control of LH release are not the result of sex differences in oestrogen sensitivity or responsiveness.
研究了暴露于长光照周期（14小时光照：10小时黑暗；14L:10D）或短光照周期（6L:18D）的雄性和雌性叙利亚仓鼠血清促黄体生成素（LH）每小时值的性别差异。在长光照周期下，雌性仓鼠因循环中高水平的雌二醇（1047.36±90.68 pmol/l）而出现发情前期LH激增，而雄性仓鼠的LH值基本保持恒定。在短光照周期饲养的雌性仓鼠中，雌二醇水平降低了五倍；然而，观察到血清LH出现离散性激增，类似于在长光照周期下的雌性仓鼠发情前期所见。尽管暴露于短光照周期消除了雌激素对LH下午激增表达的正反馈需求，但饲养在短光照周期的雄性仓鼠没有显示出血清LH下午激增的迹象。这些观察结果表明，LH释放的神经控制中的性别差异不是雌激素敏感性或反应性性别差异的结果。
