Dei Cas L, Bianchi G, Paini G P, Effendy F N, Brizzi R, Visioli O
G Ital Cardiol. 1978 Jun;8(6):612-8.
Two cases of carotid sinus syndrome with peculiar clinical and nosological characteristics are presented. The clinical symptoms were characterized by syncope with bradicardia and hypotension, which occurred contemporarily or independently of each other. The most valuable medical therapy to prevent or got over the syncopal attacks has proved to be one associating the sympathicomimetic drugs (high dosage dopamine, particularly on demande pacemaker. Complete decrease of symptoms following was obtained only after surgical treatment: denervation of carotid sinus in one case, intracranical section of the glosspharyngeal nerve and of the two vagal termination nearer to IX in the other case. This last result makes it possible to consider the case in question from an original nosological point of view exploiting the pathogenetic importance of stimulating the afferent nerve-fibres of the glossofaryngeal-nerve.
本文报告两例具有特殊临床和疾病分类学特征的颈动脉窦综合征。临床症状以伴有心动过缓和低血压的晕厥为特征，这些症状可同时出现或相互独立出现。事实证明，预防或克服晕厥发作最有效的药物治疗是联合使用拟交感神经药物（高剂量多巴胺，尤其是按需起搏器）。仅在手术治疗后症状才完全缓解：一例为颈动脉窦去神经支配，另一例为颅内切断舌咽神经及两条距舌咽神经较近的迷走神经终末支。最后的这一结果使得从一个全新的疾病分类学角度来考虑该病例成为可能，即利用刺激舌咽神经传入神经纤维在发病机制中的重要性。
