Yu J
Brain Res. 1984 Jan 2;290(1):19-23. doi: 10.1016/0006-8993(84)90731-5.
Interruption of a spinal ascending system by hemisection of the spinal cord at mid-thoracic level restores the tactile placing (TP) which is lost after bulbar pyramid section in cats. To determine the location of the ascending system in the spinal cord, partial lesions involving various dorsal, lateral, or ventral tracts were made at mid-thoracic level in cats with pyramid section. To determine the supraspinal control of the recovered TP after pyramid section and spinal cord hemisection, lesions were made in other cortical and subcortical structures essential to TP and also in cortical areas which are not normally involved in TP in cats with recovered TP. The findings demonstrate that the spinal ascending system is located in the ventral part of the lateral funiculus and that the cerebral association cortex takes over the function of motor cortex in the reorganized control of TP. A slow course of TP recovery along with no recovery of impaired distal forelimb movements resulting from pyramidotomy were also observed.
在中胸段水平对脊髓进行半横切，中断脊髓上行系统，可恢复猫延髓锥体切断后丧失的触觉放置（TP）。为确定脊髓中该上行系统的位置，对已进行锥体切断的猫在中胸段水平制作涉及不同背侧、外侧或腹侧束的部分损伤。为确定锥体切断和脊髓半横切后恢复的TP的脊髓上控制，对TP所必需的其他皮质和皮质下结构以及在TP已恢复的猫中通常不参与TP的皮质区域进行损伤。研究结果表明，脊髓上行系统位于外侧索的腹侧部分，并且大脑联合皮质在TP的重组控制中接管了运动皮质的功能。还观察到TP恢复过程缓慢，且锥体切断所致的受损前肢远端运动未恢复。
