Schneider M L
Geburtshilfe Frauenheilkd. 1978 Jun;38(6):452-6.
Seven patients with carcinoma in situ respectively epidermoid carcinoma of the vagina after treatment of analogous lesions of the cervix are presented. The seven case reports are shortly discussed. All these cases of carcinoma occurred after treatment of primary lesions with abdominal hysterectomy. As the main reason for the occurrence of secondary carcinoma of the vagina the author considers the following facts: The insufficient removal of the primary lesions, the multicentric development of carcinoma and the missed detection of a yet invasive neoplastic change at the occasion of the first disease. The results are compared to those of other authors. The observations lead the author to the following consequences: The in situ lesion of the cervix should be treated with a vaginal hysterectomy in combination with a removal of a vaginal cuff after a Schiller test. Patients with carcinoma in situ of the cervix should be followed by cytologic controls. Preinvasive lesions of the vagina should be treated surgically whereas invasive vaginal carcinoma demands radiotherapy.
本文报告了7例宫颈类似病变治疗后发生阴道原位癌或表皮样癌的患者。对这7例病例报告进行了简要讨论。所有这些阴道癌病例均发生在经腹子宫切除治疗原发性病变之后。作者认为阴道继发性癌发生的主要原因如下：原发性病变切除不充分、癌的多中心发展以及在首次发病时未检测到仍为浸润性的肿瘤性改变。将结果与其他作者的结果进行了比较。这些观察结果使作者得出以下结论：宫颈原位病变应采用阴道子宫切除术并在Schiller试验后切除阴道袖口进行治疗。宫颈原位癌患者应进行细胞学检查随访。阴道癌前病变应手术治疗，而浸润性阴道癌则需要放疗。
