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母代与子代的遗传生理关系在确定哺乳动物生存能力和繁殖力中的作用。II. 由移植囊胚发育而来的BALB、CBA和DBA品系小鼠胚胎的重量

[Role of the genetic-physiological interrelationships of mother-progeny in establishing the viability and fertility of mammals. II. The weight of the embryos of BALB, CBA and DBA strain mice developing from transplanted blastocysts].

作者信息

Evsikov V I, Morozova L M

出版信息

Genetika. 1978;14(7):1264-71.

PMID:669262
Abstract

The weights of embryos and their placentas obtained by blastocysts of CBA/LacY and DBA/2 mouse strains transfer in recipient females of BALB/c strain and also by blastocysts of BALB/c mouse strain transfer in recipient females of CBA/LacY strain were analysed on the 16th gestation day. It is shown that placental weights are determined by genotypic peculiarities of embryos, although comparative placental weights of different strain embryos could also depend on females fertility. The weight of allogenic embryos (developed from transferred blastocysts) significantly excessed the weight of singenic embryos, and most significant differences were noted in females with small number of embryos. The possibilities to solve some applied and fundamental problems of mammalian reproduction given by the method of interstrain and interbreed early stage embryos transfer are discussed.

摘要

在妊娠第16天,分析了将CBA/LacY和DBA/2小鼠品系的囊胚移植到BALB/c品系受体雌性小鼠体内所获得的胚胎及其胎盘的重量,以及将BALB/c小鼠品系的囊胚移植到CBA/LacY品系受体雌性小鼠体内所获得的胚胎及其胎盘的重量。结果表明,胎盘重量由胚胎的基因型特性决定,尽管不同品系胚胎的相对胎盘重量也可能取决于雌性的生育能力。同种异体胚胎(由移植的囊胚发育而来)的重量显著超过同基因胚胎的重量,并且在胚胎数量较少的雌性小鼠中观察到最显著的差异。讨论了通过品系间和品种间早期胚胎移植方法解决哺乳动物繁殖的一些应用和基础问题的可能性。

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