Sharma S C, Sabra A, Molloy A, Bonnar J
Hum Nutr Clin Nutr. 1984 Jan;38(1):3-9.
Levels of histamine and total ascorbic acid (L-ascorbic acid plus dehydroascorbic acid) in the peripheral blood of women in pre-eclampsia have been measured. The results show that blood histamine is increased both in the moderate and severe form of pre-eclampsia. Blood ascorbic acid on the other hand is increased only in the severe form of pre-eclampsia. The rise in histamine values may be in response to the rising blood pressure in pre-eclampsia. The rise in ascorbic acid values may reflect the reduced maternal blood volume and/or restricted transport of ascorbic acid from maternal to fetal tissues.
