Kramer D S, Drake M E
J Clin Psychiatry. 1984 Jan;45(1):40-1.
A man taking haloperidol presented with psychosis, polydipsia, and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). A water-loading test indicated that haloperidol did not cause the SIADH. In patients taking haloperidol or other neuroleptics associated with SIADH who develop psychosis, polydipsia, and complications of SIADH such as hyponatremia, water loading may be helpful in adjusting psychotropic medications so as to control psychosis while avoiding the complications of hyponatremia.
一名服用氟哌啶醇的男子出现了精神病、烦渴和抗利尿激素分泌不当综合征(SIADH)。水负荷试验表明氟哌啶醇不会导致SIADH。对于服用氟哌啶醇或其他与SIADH相关的抗精神病药物而出现精神病、烦渴以及SIADH并发症(如低钠血症)的患者,水负荷试验可能有助于调整精神药物,以便在控制精神病的同时避免低钠血症并发症。