Reed C N, Cooper P H, Swerlick R A
J Am Acad Dermatol. 1984 Jan;10(1):110-3. doi: 10.1016/s0190-9622(84)80053-5.
We describe a 69-year-old woman who developed multiple violaceous papules and nodules on both lower extremities. The clinical impression was Kaposi's sarcoma, but the lesions proved to represent multiple ectatic venules that contained papillary endothelial hyperplasia and small foci of an unorganized thrombus. The lesions persisted during a 6-month period of observation. Intravascular papillary endothelial hyperplasia can be observed as an unusual pattern of organization of arterial and venous thrombi or as a focal, incidental microscopic finding in hemangiomas. When lesions of intravascular papillary endothelial hyperplasia cause clinical signs, they characteristically appear as solitary, slowly growing nodules, usually on the upper extremities or head. Intravascular papillary endothelial hyperplasia has not previously been noted to simulate Kaposi's sarcoma.
我们描述了一位69岁女性，其双下肢出现了多个紫红色丘疹和结节。临床诊断为卡波西肉瘤，但病变经证实为多个扩张的小静脉，其中含有乳头状内皮细胞增生和小灶性无组织血栓。在6个月的观察期内，病变持续存在。血管内乳头状内皮细胞增生可表现为动脉和静脉血栓形成的一种异常组织模式，或作为血管瘤中一种局灶性、偶然的微观表现。当血管内乳头状内皮细胞增生的病变引起临床症状时，其特征性表现为孤立的、生长缓慢的结节，通常位于上肢或头部。此前尚未注意到血管内乳头状内皮细胞增生会模拟卡波西肉瘤。
