Berberich S N, Zager J R, Plotnick G D, Fisher M L
J Am Coll Cardiol. 1984 Feb;3(2 Pt 1):284-90. doi: 10.1016/s0735-1097(84)80011-x.
Echocardiographic measurements of left ventricular end-systolic dimension and fractional shortening obtained in the supine position before and immediately after maximal upright exercise were evaluated in 11 normal volunteers, 35 patients with coronary artery disease and 17 patients without coronary artery disease. The time course of recovery from acute exercise-induced changes in echocardiographic dimensions was analyzed using serial postexercise recordings from normal subjects. An exercise-induced decrease in end-systolic dimension (greater than or equal to 3 mm) and increase in fractional shortening (greater than or equal to 5%) persisted for 3 minutes or longer in the immediate postexercise period in each of the normal volunteers. With these criteria to separate normal from abnormal responses, abnormal responses were observed in 16 (94%) of 17 patients with coronary artery disease and in only 2 (6%) of 35 patients without coronary artery disease. Immediate postexercise echocardiography appears to be a practical and potentially valuable adjunct in the detection of coronary artery disease.
对11名正常志愿者、35名冠心病患者和17名无冠心病患者进行了评估，测量了他们在最大程度直立运动前和运动后即刻仰卧位时的左心室收缩末期内径和缩短分数的超声心动图参数。利用正常受试者运动后的系列记录，分析了急性运动引起的超声心动图参数变化后的恢复时间过程。在每个正常志愿者运动后的即刻，运动引起的收缩末期内径减小（大于或等于3毫米）和缩短分数增加（大于或等于5%）持续3分钟或更长时间。采用这些标准来区分正常反应和异常反应，在17名冠心病患者中有16名（94%）出现异常反应，而在35名无冠心病患者中只有2名（6%）出现异常反应。运动后即刻超声心动图似乎是检测冠心病的一种实用且可能有价值的辅助手段。
