Koch U T, Koester J, Weiss K R
J Neurophysiol. 1984 Jan;51(1):126-35. doi: 10.1152/jn.1984.51.1.126.
Previous studies have demonstrated that heart rate and blood pressure increase in Aplysia during an arousal state elicited by food stimuli. In addition, during biting, blood flow is routed alternately to the head (during protraction of the buccal mass) and to the digestive system (during retraction). In this study, cutting the pleuroabdominal connectives eliminated 75% of the heart rate response during food arousal, and cutting the pleuroabdominal connectives eliminated 20-50% of the pressor response. Recording in the abdominal ganglion from the RBHE heart excitor and the three LBVC vasoconstrictor motor neurons in a reduced preparation showed that activity in these neurons was increased 50 and 100%, respectively, during food arousal. Activity of the LBVC cells was maximal during the protraction phase of biting. The LBVC vasoconstrictor motor neurons, when fired at the rates recorded during food arousal, can occlude the abdominal aorta completely. We conclude that the RBHE and LBVC neurons mediate, in part, the heart rate and pressor responses recorded during food arousal and that cyclic activity in LBVC contributes significantly to the cyclic alternation of blood flow between the head and the gut during rhythmic biting behavior.
先前的研究表明，在由食物刺激引发的觉醒状态下，海兔的心率和血压会升高。此外，在咬食过程中，血流会交替流向头部（在口球前伸时）和消化系统（在口球回缩时）。在本研究中，切断胸腹神经连索消除了食物激发时75%的心率反应，切断胸腹神经连索消除了20%-50%的升压反应。在简化标本中，从RBHE心脏兴奋神经元和三个LBVC血管收缩运动神经元记录腹神经节活动，结果显示在食物激发期间，这些神经元的活动分别增加了50%和100%。LBVC细胞的活动在咬食的前伸阶段达到最大值。当LBVC血管收缩运动神经元以食物激发时记录的频率发放冲动时，可完全阻断腹主动脉。我们得出结论，RBHE和LBVC神经元部分介导了食物激发时记录到的心率和升压反应，并且在有节律的咬食行为期间，LBVC中的周期性活动显著促成了头部和肠道之间血流的周期性交替。
