Galantseva G F, Guseva L I, Plichko V I
Med Radiol (Mosk). 1984 Jan;29(1):57-62.
A study was made of the frequency, clinical appearance and therapeutic methods of radiation injuries in 12 out of 57 patients who were treated for cancer of the tongue using interstitial therapy with 252Cf. The most frequent radiation injuries were observed in patients (6 out of 18, i.e. 34%) who were treated for recurrent and residual tumors after previous radiotherapeutic courses as compared to the treatment of primary malignant lesions in 6 out 39 (15%) patients. The clinical picture of radiation injuries of the tongue presented an ulcer of various sizes. A clinical classification of radiation injuries of the tongue was developed depending on the degree of the manifestations. Among causative factors the most important role is played by an absorbed tumor dose which when exceeding 9 Gy in patients with primary tumors and 8 Gy in patients with recurrent and residual tumors, resulted in radiation injuries. The development of radiation injuries is also influenced by poor hygiene and the oral cavity, and such harmful habits as smoking and alcohol consumption. Conservative therapeutic measures made it possible to achieve a complete epithelization of ulcers.
对57例采用252Cf组织间治疗法治疗舌癌的患者中的12例进行了放射性损伤的频率、临床表现及治疗方法的研究。与39例（15%）原发性恶性病变患者相比，在接受过先前放疗疗程后复发性和残留性肿瘤的患者（18例中的6例，即34%）中观察到最常见的放射性损伤。舌部放射性损伤的临床表现为大小各异的溃疡。根据表现程度制定了舌部放射性损伤的临床分类。在致病因素中，吸收的肿瘤剂量起着最重要的作用，原发性肿瘤患者吸收剂量超过9 Gy、复发性和残留性肿瘤患者超过8 Gy时会导致放射性损伤。口腔卫生不良以及吸烟和饮酒等不良习惯也会影响放射性损伤的发生。保守治疗措施使溃疡得以完全上皮化。
