Loening-Baucke V A, Younoszai M K
Pediatrics. 1984 Feb;73(2):199-205.
Using three pressure transducers, motility of the lower and upper rectum and sigmoid was recorded in 18 healthy and 18 chronically constipated children. The 36 children had a wide range of values for frequency of contractions, duration, amplitude, percent of activity, and surface area under the contraction curves. The mean values for percent of activity and surface area were significantly lower in the constipated than in the control children in all three recording areas (P less than .05). Motility in the constipated children, after 2 months of treatment that included milk of magnesia, showed significant increase when compared with corresponding pretreatment values (P less than .05), and were not different from corresponding values of the control children (P greater than .1). Seven to 12 months and 3 years later, rectal and sigmoid motility remained normal. Three-year follow-up revealed that most of the constipated children were not completely free of constipation and fecal soiling in spite of normal motility. Therefore, it appears that the hypomotility in the untreated patients was the result of the chronic fecal impaction and rectal distension and while it was not the cause of the constipation, it may have contributed to its severity.
使用三个压力传感器，记录了18名健康儿童和18名慢性便秘儿童的直肠上下段及乙状结肠的运动情况。这36名儿童在收缩频率、持续时间、幅度、活动百分比以及收缩曲线下的表面积等方面具有广泛的数值范围。在所有三个记录区域中，便秘儿童的活动百分比和表面积的平均值显著低于对照组儿童（P < 0.05）。在接受包括氧化镁乳剂在内的治疗2个月后，便秘儿童的运动情况与相应的治疗前值相比有显著增加（P < 0.05），且与对照组儿童的相应值无差异（P > 0.1）。7至12个月以及3年后，直肠和乙状结肠的运动情况保持正常。三年随访显示，尽管运动正常，但大多数便秘儿童仍未完全摆脱便秘和粪便污染。因此，似乎未经治疗的患者运动减弱是慢性粪便嵌塞和直肠扩张的结果，虽然它不是便秘的原因，但可能加重了便秘的严重程度。
