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骨髓纤维化中髓外造血导致的脊髓压迫

Spinal cord compression by extramedullary haematopoiesis in myelofibrosis.

作者信息

Crawford D C, Nightingale S, Bates D, Tomlinson B E

出版信息

Postgrad Med J. 1984 Jan;60(699):62-3. doi: 10.1136/pgmj.60.699.62.

DOI:10.1136/pgmj.60.699.62
PMID:6694952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2417733/
Abstract

A 50-year-old man with a 20-year history of myelofibrosis developed mild impairment of dorsal column sensation and ataxia of gait. A myelogram and subsequent peroperative biopsy demonstrated spinal cord compression due to extramedullary haematopoiesis. There was an excellent clinical response to surgery and radiotherapy. The characteristic clinical features and the pathogenesis of this unusual complication of myelofibrosis and extramedullary haematopoiesis are discussed.

摘要

一名患有骨髓纤维化20年的50岁男性出现了轻度的脊髓后索感觉障碍和步态共济失调。脊髓造影及随后的术中活检显示,脊髓受压是由髓外造血所致。手术和放疗取得了良好的临床效果。本文讨论了骨髓纤维化和髓外造血这种不寻常并发症的特征性临床特点及发病机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20cb/2417733/518fad7f54ce/postmedj00119-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20cb/2417733/518fad7f54ce/postmedj00119-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20cb/2417733/518fad7f54ce/postmedj00119-0068-a.jpg

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引用本文的文献

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Extramedullary haemopoietic tumours complicating polycythaemia vera.真性红细胞增多症合并的髓外造血肿瘤
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本文引用的文献

1
SPINAL CORD COMPRESSION BY EXTRAMEDULLARY HAEMATOPOIESIS IN MYELOSCLEROSIS.骨髓硬化症中髓外造血引起的脊髓压迫
J Neurol Neurosurg Psychiatry. 1964 Aug;27(4):313-6. doi: 10.1136/jnnp.27.4.313.
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ROENTGEN MANIFESTATIONS OF THORACIC EXTRAMEDULLARY HEMATOPOIESIS.
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Spinal cord compression due to extramedullary hematopoiesis.髓外造血导致的脊髓压迫
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4
Spinal cord compression with paraplegia in myelofibrosis.骨髓纤维化伴截瘫的脊髓压迫症
Arch Neurol. 1980 Jun;37(6):389-90. doi: 10.1001/archneur.1980.00500550091019.
5
Hemopoiesis in the spinal epidural space; case report.
J Neurosurg. 1970 Apr;32(4):485-90. doi: 10.3171/jns.1970.32.4.0485.
6
The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with the myeloproliferative syndrome.特发性骨髓化生(AMM)的自然病史及其与骨髓增殖综合征关系的批判性评估。
Medicine (Baltimore). 1971 Sep;50(5):357-420. doi: 10.1097/00005792-197109000-00001.
7
Extramedullary hematopoiesis in the spinal epidural space.脊髓硬膜外间隙的髓外造血
J Can Assoc Radiol. 1974 Dec;25(4):297-9.