Neostriatal participation in prosencephalic systems: evidence from deoxyglucose autoradiography.

Epileptic foci, produced by small intracortical injections of penicillin, increased the uptake of 2-DG not only in the injected cortical area but also in a number of other formations. Each cortical focus coactivated specific portions of the striatum and thalamus. In certain instances, activation was found also in some other formations. These data suggest that each cortical area is related to a separate subcortical system consisting at least of specific parts of the striatum and the thalamus. The cortex-related heterogeneity of the striatum has been previously demonstrated in neurobehavioral experiments.