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用于贫血和缺铁诊断的实验室检查值的年龄相关变化。

Age-related changes in laboratory values used in the diagnosis of anemia and iron deficiency.

作者信息

Yip R, Johnson C, Dallman P R

出版信息

Am J Clin Nutr. 1984 Mar;39(3):427-36. doi: 10.1093/ajcn/39.3.427.

DOI:10.1093/ajcn/39.3.427
PMID:6695842
Abstract

Laboratory results from the Second National Health and Nutrition Examination Survey (NHANES II) were used to define age-related changes in laboratory values that are related to the diagnosis of anemia and iron deficiency. Analyses included Hb, hematocrit, red blood cell count, red cell indices, iron, total iron-binding capacity, transferrin saturation, and erythrocyte protoporphyrin. Computation of median values and 95% ranges by age and sex for each laboratory test were performed on 15,093 subjects between 1 and 74 yr of age who had complete laboratory data on venous blood, after excluding those subjects with an abnormality in one or more of three other laboratory tests. Age-related changes in laboratory measurements, such as those described herein, must be taken into consideration in order to optimize the identification of individuals with anemia and iron deficiency.

摘要

第二次全国健康与营养检查调查(NHANES II)的实验室结果被用于确定与贫血和缺铁诊断相关的实验室值的年龄相关变化。分析包括血红蛋白(Hb)、血细胞比容、红细胞计数、红细胞指数、铁、总铁结合力、转铁蛋白饱和度和红细胞原卟啉。在排除了三项其他实验室检查中一项或多项异常的受试者后,对15093名年龄在1至74岁之间且有静脉血完整实验室数据的受试者,按年龄和性别对每项实验室检查进行中位数和95%范围的计算。为了优化对贫血和缺铁个体的识别,必须考虑本文所述的实验室测量中的年龄相关变化。

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