作为区分α地中海贫血特征与缺铁性贫血手段的游离红细胞原卟啉微量测定
The micromeasurement of free erythrocyte protoporphyrin as a means of differentiating alpha thalassemia trait from iron deficiency anemia.
作者信息
Koenig H M, Lightsey A L, Schanberger J E
出版信息
J Pediatr. 1975 Apr;86(4):539-41. doi: 10.1016/s0022-3476(75)80143-0.
Free erythrocyte protoporphyrin levels were measured in 29 individuals with alpha thalassemia trait, 19 with proved iron deficiency anemia, and 25 normal control subjects. Individuals with alpha thalassemia trait and normal iron studies had FEP levels in the normal range despite marked degrees of microcytosis. In contrast, individuals with iron deficiency anemia had marked elevation of FEP levels with similar degrees of microcytosis. Measurement of FEP levels appears to be a useful tool in differentiating alpha thalassemia trait from iron deficiency anemia.
对29例α地中海贫血特征患者、19例确诊为缺铁性贫血的患者以及25名正常对照者测定了游离红细胞原卟啉水平。具有α地中海贫血特征且铁代谢检查正常的个体，尽管存在明显程度的小红细胞症，但其FEP水平仍在正常范围内。相比之下，缺铁性贫血患者的FEP水平显著升高，且小红细胞症程度相似。测定FEP水平似乎是区分α地中海贫血特征与缺铁性贫血的有用工具。
Zotero 插件