Gittenberger-de Groot A C, Wenink A C
Br Heart J. 1984 Mar;51(3):252-8. doi: 10.1136/hrt.51.3.252.
The morphological characteristics of mitral atresia were studied in 30 hearts to determine the presence or absence of a morphological rudiment of the atretic valve and the relation of this rudiment, if found, to any chamber in the ventricular mass. All the hearts showed atrial situs solitus and no ventricular inversion; consequently all had left atrioventricular atresia. In all instances dense fibrous tissue connected the floor of the left atrium to the left ventricle. This connective tissue is considered to be the morphological rudiment of the atretic mitral valve. In several hearts the intervening fibrous tissue varied from a thick fibrous membrane to a tiny fibrous cord; it is impossible to detect these variations clinically. It is, therefore, more practical to classify those hearts which have a detectable fibrous membrane macroscopically as having an "imperforate membrane" and those with a fibrous strand detectable only microscopically as having an "absent atrioventricular connection."
对30颗心脏的二尖瓣闭锁形态特征进行了研究，以确定闭锁瓣膜形态残迹的有无，以及如果发现这种残迹，它与心室团中任何腔室的关系。所有心脏均显示心房正位且无心室反位；因此均为左房室闭锁。在所有病例中，致密的纤维组织将左心房底部与左心室相连。这种结缔组织被认为是闭锁二尖瓣的形态残迹。在几颗心脏中，其间的纤维组织从厚纤维膜到细纤维索不等；临床上无法检测到这些差异。因此，将那些宏观上可检测到纤维膜的心脏归类为“膜闭锁”，而将那些仅在显微镜下可检测到纤维束的心脏归类为“房室连接缺如”更为实用。
