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[大鼠中主动脉的长期培养及分化型平滑肌血管细胞特性的保留]

[Long-term culture of the rat medial aorta with preservation of the characteristic properties of differentiated smooth muscle vascular cells].

作者信息

Il'inskiĭ O B, Kliueva T S, Krasnikova T L, Printseva O Iu, Solov'eva A I

出版信息

Biull Eksp Biol Med. 1984 Feb;97(2):183-5.

PMID:6696986
Abstract

The authors provide the results of a long-term cultivation (106 passages during 2 years) of smooth muscle cells of rat aorta media, where the cells preserve the signs characteristic for their differentiation: ability to contract, specific ultrastructure (the presence of the caveole series, microfilaments of 4-6 nm, intermediate filaments of 10 nm, dark bodies in the cytoplasm), and ability to synthesize the alpha-form of actin specific for smooth muscle vascular cells.

摘要

作者给出了大鼠主动脉中膜平滑肌细胞长期培养(2年内传代106次)的结果,这些细胞保留了其分化特征:收缩能力、特定的超微结构(存在小窝系列、4 - 6纳米的微丝、10纳米的中间丝、细胞质中的暗体)以及合成血管平滑肌细胞特有的α-肌动蛋白的能力。

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[Long-term culture of the rat medial aorta with preservation of the characteristic properties of differentiated smooth muscle vascular cells].[大鼠中主动脉的长期培养及分化型平滑肌血管细胞特性的保留]
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