Huben R P, Williams P D, Pontes J E, Panahon A M, Murphy G P
Cancer. 1984 Apr 1;53(7):1451-5. doi: 10.1002/1097-0142(19840401)53:7<1451::aid-cncr2820530704>3.0.co;2-u.
A retrospective study of all cases of seminoma treated at Roswell Park Memorial Institute from 1970 through 1979 was conducted. Fifty-six evaluable patients treated initially with radiation therapy were seen during this period, and the overall survival rate at an average follow-up period of 52 months was 82%. The survival rate in patients with bulky abdominal or supradiaphragmatic metastases was only 33% (4 of 12 patients). Treatment failures were analyzed to determine their apparent causes and the implication of such failures to the future management of seminoma. The use of combination chemotherapy as the initial treatment modality in advanced seminoma is discussed in light of these results.
对1970年至1979年在罗斯韦尔公园纪念研究所接受治疗的所有精原细胞瘤病例进行了一项回顾性研究。在此期间，有56例最初接受放射治疗的可评估患者，平均随访52个月时的总生存率为82%。腹部肿块或膈上转移患者的生存率仅为33%（12例患者中的4例）。对治疗失败情况进行了分析，以确定其明显原因以及此类失败对精原细胞瘤未来治疗的影响。根据这些结果，讨论了联合化疗作为晚期精原细胞瘤初始治疗方式的应用。
