Ketiku K K, Durosinmi-Etti F A
Clin Radiol. 1984 Mar;35(2):155-8. doi: 10.1016/s0009-9260(84)80023-9.
Kaposi's sarcoma is known to be multicentric in origin. It starts predominantly on the skin but visceral organs can be involved as well. Previous experience in the management of this condition in Lagos, Nigeria has been based mainly on the use of local radiotherapy. A better understanding of the natural history and clinicopathological features of this disease has given prominence to the use of chemotherapy and this is now being advocated as the first line of management in most cases in place of radiotherapy. Experience and results of the use of multiple chemotherapy in 10 cases seen at the Lagos University Teaching Hospital between 1976 and 1982 are discussed. Seven patients (70%) showed complete tumour regression, two (20%) had partial response and one (10%) did not respond.
卡波西肉瘤已知起源于多中心。它主要起始于皮肤,但内脏器官也可能受累。以往在尼日利亚拉各斯处理这种疾病的经验主要基于局部放疗的使用。对该疾病自然史和临床病理特征的更好理解突出了化疗的应用,现在在大多数情况下,化疗被提倡作为一线治疗方法来取代放疗。本文讨论了1976年至1982年间在拉各斯大学教学医院所见的10例患者使用多种化疗的经验和结果。7例患者(70%)肿瘤完全消退,2例(20%)部分缓解,1例(10%)无反应。