Kaplun A, Griffel B, Halperin B, Aronson M
Eur Surg Res. 1984;16(2):131-5. doi: 10.1159/000128399.
An experimental model for inducing peritoneal adhesions in mice is described. Measurable thermal trauma can be inflicted by the application of a heated metal object, for a given lapse of time, to the surface of a section of mouse intestine. Parameters of temperature, area and application time were so manipulated as to obtain adhesions in only 70-75% of treated mice. It is maintained that this model can enable better evaluation of various prophylactic means and also the detection of exacerbating agents.
本文描述了一种在小鼠中诱导腹膜粘连的实验模型。通过将加热的金属物体在给定的时间内应用于小鼠肠段表面，可以造成可测量的热损伤。对温度、面积和应用时间等参数进行了调整，以便仅在70-75%的受试小鼠中产生粘连。有人认为，该模型能够更好地评估各种预防手段，也能够检测出加重病情的因素。
