Kusielewicz D, Conte-Marti J, Parc R, Darnis F, Bodin F
Gastroenterol Clin Biol. 1984 Jan;8(1):33-5.
A case of extensive squamous cell carcinoma of the esophagus in a 56 year old man, with an history of excessive alcoholic and tobacco consumption, is reported. After subtotal esophagectomy, the course was favorable 10 months after surgery. The pathological study of the surgical specimen showed that the tumor was superficial and confined to the mucosa and submucosa. The lesion measured 65 mm in length (after fixation) and was circumferential. Foci of moderate and severe dysplasia and inflammatory erosions were also observed. The relationship between extensive squamous cell carcinoma, dysplasia, esophagitis and the concept of "carcinogenic fields" are discussed. The necessity of large radical resection of the esophagus is emphasized.
报告了一例56岁男性食管广泛鳞状细胞癌病例,该患者有过量饮酒和吸烟史。行食管次全切除术后,术后10个月病情良好。手术标本的病理研究显示,肿瘤为浅表性,局限于黏膜和黏膜下层。病变长度为65毫米(固定后),呈环形。还观察到中度和重度发育异常灶及炎性糜烂。讨论了广泛鳞状细胞癌、发育异常、食管炎与“致癌区域”概念之间的关系。强调了食管大根治性切除术的必要性。