Stone T
Int J Epidemiol. 1984 Mar;13(1):58-64. doi: 10.1093/ije/13.1.58.
Endemic goitre in adult females, cretinism, and anthropometry in children were examined in a goitrous area of Bangladesh. An area survey showed total goitre varying from 62.0 to 93.0%, visible goitre from 9.0 to 54.8% between areas. A village study examining thyroid size in 538 adult females and anthropometry in 116 children showed goitre prevalences varying significantly (p less than 0.001) but unpredictably with household landholding size; underweight and wasting varied inversely and significantly (p less than 0.01 and 0.05 respectively) with the same socioeconomic indicator. By household, there was no relationship between anthropometry in children and thyroid enlargement in the mother. Hormone analyses showed depressed serum T4, but no raised TSH. Only one deaf-mute cretin was found in the area. It is speculated that variation in goitre prevalence in this moderately severe endemic primarily reflects qualitative and quantitative changes in diet, as a function of the socioeconomic status of the household.
在孟加拉国的一个甲状腺肿流行地区，对成年女性的地方性甲状腺肿、呆小症以及儿童的人体测量学指标进行了研究。一项地区调查显示，不同地区的甲状腺肿总患病率在62.0%至93.0%之间，可见性甲状腺肿患病率在9.0%至54.8%之间。一项针对538名成年女性甲状腺大小和116名儿童人体测量学指标的村庄研究表明，甲状腺肿患病率差异显著（p<0.001），但与家庭土地拥有规模之间的关系不可预测；体重不足和消瘦与同一社会经济指标呈显著负相关（分别为p<0.01和0.05）。就家庭而言，儿童的人体测量学指标与母亲的甲状腺肿大之间没有关系。激素分析显示血清T4水平降低，但促甲状腺激素（TSH）没有升高。该地区仅发现一名聋哑型呆小症患者。据推测，在这种中度严重的地方病中，甲状腺肿患病率的差异主要反映了饮食在质量和数量上的变化，这是家庭社会经济地位的一个函数。
