Quigley A J, Bredemeyer D E, Seow S S
Med J Aust. 1984 Mar 31;140(7):425-6. doi: 10.5694/j.1326-5377.1984.tb108106.x.
Buprenorphine is a powerful new analgesic agent with agonist and antagonist opiate receptor activity. Its withdrawal symptoms have been reported as being mild; however, its potential for abuse is not known. A case of buprenorphine abuse is reported, in which the patient's history and his response to naloxone suggest that important underlying factors were physical tolerance and dependence.
丁丙诺啡是一种具有激动和拮抗阿片受体活性的强效新型镇痛药。据报道,其戒断症状较轻;然而,其滥用潜力尚不清楚。本文报告了一例丁丙诺啡滥用病例,该患者的病史及对纳洛酮的反应表明,身体耐受性和依赖性是重要的潜在因素。