B.M. Tripathi, MD., Additional Professor, Department of Psychiatry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029.
Indian J Psychiatry. 1995 Jan;37(1):23-5.
The increasing use of buprenorphine among drug dependent subjects demands systematic enquiry into the clinical profile of buprenorphine withdrawal. Six male buprenorphine dependent (parenteral) subjects were observed for opiate withdrawal over a two week period. The onset of withdrawal occurred 48 hours after the last dose, peaked around the third day and lasted up to ten days. The withdrawals were similar to morpliine type drugs and moderate in intensity.
阿片类药物依赖者中丁丙诺啡的应用日益广泛,因此有必要对丁丙诺啡戒断的临床特征进行系统研究。我们观察了 6 例丁丙诺啡依赖(注射)者,在 2 周的时间内出现阿片类药物戒断症状。停药后 48 小时出现戒断症状,第 3 天达高峰,持续 10 天左右。戒断症状与吗啡类药物相似,程度中等。