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妊娠期室上性心动过速:维拉帕米转复心律

Supraventricular tachycardia in pregnancy: cardioversion with verapamil.

作者信息

Klein V, Repke J T

出版信息

Obstet Gynecol. 1984 Mar;63(3 Suppl):16S-18S.

PMID:6700874
Abstract

Cardiac arrhythmias are not uncommon during pregnancy. The supraventricular tachyarrhythmias have been treated successfully with digoxin, propranolol, overdrive atrial pacing, electrocardioversion, and most recently with verapamil. Verapamil is the prototype calcium channel blockers. Its use in pregnancy has been limited though the experimental effects of verapamil on fetal heart activity and uterine contractility have been studied. Reported is a case of a digitalized hyperthyroid pregnant patient successfully treated with verapamil for supraventricular tachycardia. Continuous electronic fetal monitoring was used during the period of cardioversion. The excellent response to verapamil with its apparent absence of adverse maternal or fetal side effects would suggest that the use of verapamil in the treatment of supraventricular arrhythmias in pregnancy is safe and effective.

摘要

心律失常在孕期并不罕见。室上性快速心律失常已成功地用洋地黄、普萘洛尔、超速心房起搏、心脏电复律进行治疗,最近还用维拉帕米进行治疗。维拉帕米是钙通道阻滞剂的原型。尽管已经研究了维拉帕米对胎儿心脏活动和子宫收缩的实验性影响,但其在孕期的使用一直受到限制。本文报道了1例用维拉帕米成功治疗室上性心动过速的洋地黄化甲亢孕妇病例。在心脏复律期间使用了连续电子胎儿监护。维拉帕米疗效极佳,且明显没有母体或胎儿不良副作用,这表明维拉帕米用于治疗孕期室上性心律失常是安全有效的。

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