Bush J K, Givner L B, Whitaker S H, Anderson D C, Percy A K
Pediatrics. 1984 Mar;73(3):343-7.
Necrotizing fasciitis is characterized by necrosis with extension over fascial planes and mixed aerobic-anaerobic etiologies. Necrotizing fasciitis is uncommon in children and seldom involves the head and neck area. An infant who developed necrotizing fasciitis involving the parapharyngeal space is described. Chronic dental pathology was probably the initial focus of infection. The patient had a left hemiparesis due to a right middle cerebral artery infarct. Carotid angiography demonstrated complete occlusion of the right internal carotid artery, probably secondary to inflammatory arteritis or direct compression along its course through the parapharyngeal space. Mixed aerobic-anaerobic etiologies predominate in infections of the potential spaces of the head and neck as was demonstrated in this patient. The patient recovered, but had neurologic sequelae. Prompt and aggressive therapy is necessary in patients with necrotizing fasciitis syndromes in order to avoid such severe complications.
坏死性筋膜炎的特征是坏死并沿筋膜平面扩散,病因是需氧菌与厌氧菌混合感染。坏死性筋膜炎在儿童中并不常见,很少累及头颈部区域。本文描述了一名发生咽旁间隙坏死性筋膜炎的婴儿。慢性牙齿病变可能是最初的感染灶。该患者因右侧大脑中动脉梗死而出现左侧偏瘫。颈动脉血管造影显示右侧颈内动脉完全闭塞,可能继发于炎症性动脉炎或其在通过咽旁间隙行程中的直接受压。正如该患者所示,需氧菌与厌氧菌混合感染在头颈部潜在间隙感染中占主导地位。患者康复,但遗留神经后遗症。对于患有坏死性筋膜炎综合征的患者,及时且积极的治疗是必要的,以避免此类严重并发症。