海绵状淋巴样骨髓纤维化作为毛细胞白血病的预测指标或无毛细胞的毛细胞白血病变体？

Spongy lymphoid myelofibrosis as a predictor of hairy cell leukaemia or a variant of hairy cell leukaemia without hairy cells?

作者信息

Hasselbalch H, Lisse I, Berild D, Videbaek A

出版信息

Scand J Haematol. 1984 Feb;32(2):135-44. doi: 10.1111/j.1600-0609.1984.tb02168.x.

DOI:10.1111/j.1600-0609.1984.tb02168.x

Abstract

8 patients with clinical and haematological features suggestive of hairy cell leukaemia are described. During their initial illness morphologic and cytochemical evidence of hairy cell leukaemia were lacking in all but 2 patients. A common highly characteristic histopathologic finding was reticulin fibrosis in the bone marrow, present in all patients at first presentation. The term spongy lymphoid myelofibrosis is proposed for such cases, which may represent a variant type of hairy cell leukaemia or an early stage of the disease.

摘要

本文描述了8例具有毛细胞白血病临床和血液学特征的患者。在疾病初期，除2例患者外，其余患者均缺乏毛细胞白血病的形态学和细胞化学证据。一个常见的高度特征性组织病理学发现是骨髓中的网状纤维组织增生，所有患者初诊时均存在。对于此类病例，建议使用“海绵状淋巴样骨髓纤维化”这一术语，其可能代表毛细胞白血病的一种变异类型或疾病的早期阶段。