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平衡麻醉:布托啡诺与吗啡的比较

Balanced anesthesia: a comparison of butorphanol and morphine.

作者信息

Sung Y F, Weinstein M S, Ghani G A

出版信息

South Med J. 1984 Feb;77(2):180-2. doi: 10.1097/00007611-198402000-00013.

Abstract

We did a retrospective study to compare butorphanol with morphine for use in a balanced anesthetic technique with nitrous oxide, oxygen, and neuromuscular relaxants. Patient records were reviewed for preoperative, intraoperative, and postoperative arterial blood gas values and vital signs; postoperative analgesia, nausea, vomiting, hallucinations, and dysphoria; and patient recall of the procedure. Patients in the butorphanol group proved to have less postoperative respiratory depression as determined by arterial carbon dioxide tension on arrival in the recovery room (42.8 mm Hg vs 51.1 mm Hg). The patients who received butorphanol also had less nausea (8.3% vs 44.4%) and less vomiting (8.3% vs 33.3%) than those given morphine. Neither group had any recall of procedure, hallucination, or dysphoria as determined by postoperative interview.

摘要

我们进行了一项回顾性研究,比较布托啡诺与吗啡在与氧化亚氮、氧气和神经肌肉松弛剂联合使用的平衡麻醉技术中的应用。对患者记录进行了审查,内容包括术前、术中和术后的动脉血气值及生命体征;术后镇痛、恶心、呕吐、幻觉和烦躁不安情况;以及患者对手术过程的回忆。结果显示,根据恢复室中动脉二氧化碳分压判断,布托啡诺组患者术后呼吸抑制较轻(42.8毫米汞柱对51.1毫米汞柱)。与接受吗啡的患者相比,接受布托啡诺的患者恶心(8.3%对44.4%)和呕吐(8.3%对33.3%)情况也较少。术后访谈结果显示,两组患者均未出现手术过程回忆、幻觉或烦躁不安情况。

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