Liebenstein J, Noack E J, Hettenbach A, Bauknecht H
Zentralbl Gynakol. 1984;106(3):160-9.
Records of 256 patients with carcinoma of the cervix uteri stage T1b from the years 1965-1979 were reviewed retrospectively. By screening programs only 21% were detected. Most of the neoplasms were squamous cell carcinoma (81%). The majority of the patients was treated surgically most frequently by radical hysterectomy (Wertheim-Meigs). If the carcinoma was poorly differentiated and/or lymphonodi were positive postoperative radiotherapy was added. Thus only 43 patients had no radiotherapy. 5 year survival rate could be studied in 151 patients. 89% survived 5 years or more following primary treatment. Older women (over 40 years old) showed a better prognosis than those below 40. Patients treated by radiotherapy alone survived 5 years in 88 per cent. Patients treated by radical hysterectomy had a five year survival rate of 94.6%. No difference in prognosis was observed, if radiotherapy was added. There was no significant difference in the frequency of severe complications in both kinds of treatment. The rate of recurrencies was 9.4 per cent.
回顾性分析了1965年至1979年间256例子宫颈癌T1b期患者的记录。通过筛查项目仅检测出21%的病例。大多数肿瘤为鳞状细胞癌（81%）。大多数患者接受手术治疗，最常见的是根治性子宫切除术（韦特海姆-梅格斯手术）。如果癌组织分化差和/或淋巴结阳性，则术后加用放疗。因此，只有43例患者未接受放疗。对151例患者进行了5年生存率研究。初次治疗后，89%的患者存活5年或更长时间。年龄较大的女性（40岁以上）预后比40岁以下的女性更好。单纯接受放疗的患者5年生存率为88%。接受根治性子宫切除术的患者5年生存率为94.6%。加用放疗后，预后无差异。两种治疗方式的严重并发症发生率无显著差异。复发率为9.4%。
