[Concentration of histamine in the cerebrospinal fluid of patients with cerebral circulatory disorders].

Using the spectrofluorimetric technique, histamine levels in the cerebrospinal fluid were studied in 26 patients, including 22 with impaired cerebral circulation. Correlations were established between the concentration of histamine in the cerebrospinal fluid, the underlying illness, the localization of the impairment focus and the severity of the disease course. The results obtained suggest that histamine, along with other neurohumoral factors, is involved in the system of the pathophysiological mechanisms determining the development and the course of cerebrovascular diseases.