Panush R S, Yonker R A
Am Fam Physician. 1984 Mar;29(3):258-62.
All nonsteroidal anti-inflammatory drugs act by inhibiting prostaglandin synthesis, but the particular agent that will best suit an individual patient's needs cannot be predicted. Each drug should be tried for at least three weeks at maximal dosage before it is considered ineffective. When a particular nonsteroidal anti-inflammatory agent is not effective, one from another class should be tried. Levels of drugs metabolized by the liver are altered by nonsteroidal anti-inflammatory agents. Costs are quite variable.
所有非甾体抗炎药均通过抑制前列腺素合成发挥作用，但无法预测哪种特定药物最适合个体患者的需求。每种药物在被认为无效之前，应至少以最大剂量试用三周。当一种特定的非甾体抗炎药无效时，应试用另一类中的药物。非甾体抗炎药会改变经肝脏代谢的药物水平。费用差异很大。
