Brugada P, Heddle B, Green M, Wellens H J
Am Heart J. 1984 Apr;107(4):685-97. doi: 10.1016/0002-8703(84)90316-8.
To evaluate factors playing a role in initiation of atrioventricular (AV) nodal reentrant tachycardia utilizing anterogradely a slow and retrogradely a fast conducting AV nodal pathway, 38 patients having no accessory pathways and showing discontinuous anterograde AV nodal conduction curves during atrial stimulation were studied. Twenty-two patients (group A) underwent an electrophysiologic investigation because of recurrent paroxysmal supraventricular tachycardia (SVT) that had been electrocardiographically documented before the study. Sixteen patients (group B) underwent the study because of a history of palpitations (15 patients) or recurrent ventricular tachycardia (one patient); in none of them had SVT ever been electrocardiographically documented before the investigation. Twenty-one of the 22 patients of group A demonstrated continuous retrograde conduction curves during ventricular stimulation. In 20 tachycardia was initiated by either a single atrial premature beat (18 patients) or by two atrial premature beats. Fifteen of the 16 patients of group B had discontinuous retrograde conduction curves during ventricular stimulation, with a long refractory period of their retrograde fast pathway. Tachycardia was initiated by multiple atrial premature beats in one patient. Thirteen out of the remaining 15 patients received atropine. Thereafter tachycardia could be initiated in three patients by a single atrial premature beat, by two atrial premature beats in one patient, and by incremental atrial pacing in another patient. In the remaining eight patients tachycardia could not be initiated. Our observations indicate that the pattern of ventriculoatrial conduction found during ventricular stimulation is a marker for ease of initiation of AV nodal tachycardia in patients with discontinuous anterograde AV nodal conduction curves.
为了评估在利用一条缓慢的前向房室结传导路径和一条快速的逆向房室结传导路径引发房室结折返性心动过速过程中起作用的因素,对38例无附加旁路且在心房刺激时呈现不连续前向房室结传导曲线的患者进行了研究。22例患者(A组)因反复阵发性室上性心动过速(SVT)接受电生理检查,该SVT在研究前已通过心电图记录。16例患者(B组)因有心悸病史(15例)或反复室性心动过速(1例)接受该研究;在研究前,他们中无一例通过心电图记录到SVT。A组22例患者中的21例在心室刺激时呈现连续的逆向传导曲线。在20例中,心动过速由单个房性早搏(18例患者)或两个房性早搏引发。B组16例患者中的15例在心室刺激时具有不连续的逆向传导曲线,其逆向快速传导路径的不应期较长。1例患者的心动过速由多个房性早搏引发。其余15例患者中的13例接受了阿托品治疗。此后,3例患者可由单个房性早搏引发心动过速,1例患者可由两个房性早搏引发心动过速,另1例患者可由递增性心房起搏引发心动过速。其余8例患者无法引发心动过速。我们的观察结果表明,在心室刺激时发现的室房传导模式是具有不连续前向房室结传导曲线的患者中房室结心动过速引发难易程度的一个标志。