Hack M, Merkatz I R, McGrath S K, Jones P K, Fanaroff A A
Am J Dis Child. 1984 Apr;138(4):370-5. doi: 10.1001/archpedi.1984.02140420036013.
Clinical correlates of catch-up growth were documented in 182 very-low-birth-weight (VLBW) infants (less than 1.5 kg) followed up prospectively until a corrected age of 33 months. At birth, 147 infants had weights appropriate for gestational age (AGA), and 35 were small for gestational age (SGA). The infants in each group were categorized as small if body weight was 2 SDs below the mean for age or appropriate if body weight was within 2 SDs of the mean at birth and at corrected ages of 40 weeks and 8, 21, and 33 months. Of the 147 AGA infants, 67 (46%) weighed less than 2 SDs of the mean for age at a corrected age of 40 weeks, 40 (27%) at 8 months, 28 (19%) at 21 months, and 25 (17%) at 33 months. Of the 35 SGA infants, 32 (91%) had subnormal weight at 40 weeks, 17 (49%) at 8 months and 21 months, and 16 (46%) at 33 months. Significant correlates of poor catch-up growth in the AGA group were birth weight, gestational age, severity of neonatal complications, poor neonatal head growth, and chronic physical and neurologic sequelae. In the infants in the SGA group, the correlates of poor catch-up growth were birth weight, multiple birth, and social class.
对182名极低出生体重（小于1.5千克）婴儿进行了前瞻性随访，直至矫正年龄33个月，记录了追赶生长的临床相关因素。出生时，147名婴儿体重适于胎龄（AGA），35名婴儿小于胎龄（SGA）。如果出生体重、40周矫正年龄、8个月、21个月和33个月矫正年龄时的体重低于同年龄均值2个标准差，则每组中的婴儿被分类为体重低；如果体重在均值的2个标准差范围内，则分类为体重正常。在147名AGA婴儿中，67名（46%）在40周矫正年龄时体重低于同年龄均值2个标准差，40名（27%）在8个月时低于，28名（19%）在21个月时低于，25名（17%）在33个月时低于。在35名SGA婴儿中，32名（91%）在40周时体重低于正常，17名（49%）在8个月和21个月时低于正常，16名（46%）在33个月时低于正常。AGA组追赶生长不良的显著相关因素为出生体重、胎龄、新生儿并发症严重程度、新生儿头部生长不良以及慢性身体和神经后遗症。在SGA组婴儿中，追赶生长不良的相关因素为出生体重、多胎妊娠和社会阶层。
