Gyang E O, Stevens J B, Olson W G, Tsitsamis S D, Usenik E A
Am J Vet Res. 1984 Jan;45(1):175-7.
Phagocytosis and killing of Staphylococcus aureus by polymorphonuclear leukocytes (PMN) from 8 selenium (Se)-deficient dairy cows from Wisconsin was compared with that in 5 Se-vitamin E injected dairy cows from the same herd. There was no significant difference in the ability of the PMN to phagocytize bacteria. However, PMN of Se-vitamin E injected cows killed the phagocytized bacteria significantly (P less than 0.025) better than did PMN from Se-deficient cows. The defect in the killing capability of PMN of Se-deficient cows might be due to reduced dihydronicotinamide adenine dinucleotide phosphate concentration as a result of diminished glutathione peroxidase activity due to Se-deficiency.
将来自威斯康星州的8头缺硒奶牛的多形核白细胞（PMN）对金黄色葡萄球菌的吞噬作用和杀灭作用，与同一牛群中5头注射了硒 - 维生素E的奶牛的PMN进行了比较。PMN吞噬细菌的能力没有显著差异。然而，注射了硒 - 维生素E的奶牛的PMN对吞噬细菌的杀灭效果明显（P小于0.025）优于缺硒奶牛的PMN。缺硒奶牛的PMN杀灭能力缺陷可能是由于缺硒导致谷胱甘肽过氧化物酶活性降低，从而使磷酸二氢烟酰胺腺嘌呤二核苷酸浓度降低所致。
