Burkard R, Deegan D
Audiology. 1984;23(1):85-98. doi: 10.3109/00206098409072824.
Brainstem evoked responses were obtained to 60-dB nHL clicks and click pairs presented at 27/s. Paired-click intervals ranged from 9.8 to 0.5 ms. 6 normal-hearing young adults served as subjects. Derived responses were obtained by digital response subtraction of single-click from paired-click responses. Wave V was observed to unsubtracted click 2 of the click pair at paired-click intervals down to 4 ms. Wave V of the derived (subtracted) click 2 response was observed for paired-click intervals down to 1 ms. To assess additivity, the click 1 response of the click pair was compared to the single-click response, and the unsubtracted click 2 response was compared to the derived click 2 response. At longer paired-click intervals, wave V latency was greater for click 1 of the click pair than for the single-click response. This latency difference decreases at shorter paired-click intervals and is attributed to adaptation of click 1 by click 2 of the previous pair. Wave V amplitudes for single-click and paired-click click 1 responses were not significantly different at any paired-click interval. The latency and amplitude for unsubtracted click 2 and derived click 2 responses were not significantly different at any paired-click interval. It is concluded that the responses to click 1 and click 2 of the paired clicks are additive, at least at very brief paired-click intervals.
对以27次/秒呈现的60分贝正常听力级（nHL）短声及短声对进行脑干诱发反应测试。短声对的间隔时间范围为9.8至0.5毫秒。6名听力正常的年轻成年人作为受试者。通过将短声对反应中的单次短声反应进行数字相减来获得差值反应。在短声对间隔时间低至4毫秒时，在未相减的短声对中的第二个短声（即短声2）上观察到了V波。在短声对间隔时间低至1毫秒时，观察到了差值（相减后）的短声2反应的V波。为了评估相加性，将短声对中的第一个短声（即短声1）反应与单次短声反应进行比较，并将未相减的短声2反应与差值后的短声2反应进行比较。在较长的短声对间隔时间时，短声对中短声1的V波潜伏期比单次短声反应的潜伏期更长。这种潜伏期差异在较短的短声对间隔时间时减小，这归因于前一对短声中的短声2对短声1的适应性影响。在任何短声对间隔时间下，单次短声和短声对中短声1反应的V波振幅均无显著差异。在任何短声对间隔时间下，未相减的短声2和差值后的短声2反应的潜伏期和振幅均无显著差异。得出的结论是，至少在非常短的短声对间隔时间下，对短声对中短声1和短声2的反应是相加的。
