Plesko M M, Richardson A
Biochem Biophys Res Commun. 1984 Feb 14;118(3):730-5. doi: 10.1016/0006-291x(84)91455-4.
Ultraviolet-induced unscheduled DNA synthesis was studied as a function of age in hepatocytes isolated from 6- to 32-months-old rats. Unscheduled DNA synthesis was measured by both DNA specific activity and autoradiography. Using both procedures, a significant decline in unscheduled DNA synthesis was observed after 14 months of age.