在制备用于痰液中恶性细胞检测的细胞材料时使用黏液溶解剂（Cytoclair）。
Use of a mucolytic agent (Cytoclair) in the preparation of cell material for the detection of malignant cells in sputum.
作者信息
Grainger J M, Husain O A
出版信息
J Clin Pathol. 1978 Jun;31(6):585-90. doi: 10.1136/jcp.31.6.585.
A mucolytic agent, methyl cysteine HC1 (Cytoclair), has been used to obtain a centrifuged cell deposit for the detection of malignant cells in sputum. In 178 sputum samples from 52 patients with primary lung cancer there was a slightly higher rate of detection with the mucolytic method than with the routine method: 54 positives from 27 patients compared with 48 positives from 24 patients. Morphological studies using the mucolytic agent indicated that a millipore filter with fixation of cells in suspension produces a satisfactory cell preparation and is valuable in certain problem cases.
一种黏液溶解剂，盐酸半胱氨酸甲酯（Cytoclair），已被用于获取离心后的细胞沉淀物，以检测痰液中的恶性细胞。在来自52例原发性肺癌患者的178份痰液样本中，黏液溶解法的检测率略高于常规方法：27例患者中有54例阳性，而24例患者中有48例阳性。使用黏液溶解剂的形态学研究表明，带有悬浮细胞固定装置的微孔滤膜可制备出令人满意的细胞样本，在某些疑难病例中很有价值。
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