Oron U, Alter A
Clin Orthop Relat Res. 1984 May(185):295-300.
Corrosion in metal implants (stainless steel 316L) was followed up in 25 rats for periods of 1.5 to 14.0 months after insertion into the femur, back muscles, or as an external fixation of the tibia using light and scanning electron microscopy. In the implants buried in the back muscles and as an external fixation, mainly "face" and pitting corrosion were detected in 90% of the implants, while in the intramedullary implants crevice, pitting and various "holes" of irregular shape were evident in all implants. Calcium and phosphate deposits were also found on the intrafemoral implants. The corrosion in the implants was detected as early as 1.5 months but was quite variable. However, a progressive increase in the corrosion occurred concomitant with the length of time after implantation. The question is whether stainless steel metal implants presently in clinical use can be considered innocuous.
对25只大鼠体内的金属植入物（316L不锈钢）进行了随访，这些植入物分别植入股骨、背部肌肉或用于胫骨外固定，植入后1.5至14.0个月，采用光学显微镜和扫描电子显微镜进行观察。在埋于背部肌肉和用作外固定的植入物中，90%的植入物主要检测到“表面”腐蚀和点蚀，而在髓内植入物中，所有植入物均可见缝隙腐蚀、点蚀和各种不规则形状的“孔洞”。在股骨内植入物上也发现了钙和磷的沉积。植入物的腐蚀最早在1.5个月时就被检测到，但变化很大。然而，随着植入后时间的延长，腐蚀逐渐加剧。问题是目前临床使用的不锈钢金属植入物是否可以被认为是无害的。
