Ryan J R, Begeman P C
Clin Orthop Relat Res. 1984 May(185):306-10.
Three studies were performed using paired cadaver femurs to determine the effectiveness of filling large lytic defects of the femur with methylmethacrylate. In the first test, the paired femurs were prepared with a 2.5 cm defect in the femoral cortex. One of the paired femur defects was then filled with methylmethacrylate, while the other femur was left unfilled. The femurs were then tested in axial loading until failure. In the second test the paired femurs were prepared in the same manner and tested in torque until failure. In the third test, one of the paired femurs was prepared with a 2.5 cm defect and filled with methylmethacrylate while the other femur was left intact. When comparing those femurs whose defect was filled with methylmethacrylate to the prepared femurs that remained untreated, a significant increase in axial load strength of approximately 50% and an increase in torque strength of approximately 70% was found. It would seem that filling large lytic defects with methylmethacrylate at the time of internal fixation would significantly increase strength in both axial and torsional loadings.
进行了三项研究，使用成对的尸体股骨来确定用甲基丙烯酸甲酯填充股骨大的溶骨性缺损的有效性。在第一次测试中，成对的股骨在股骨皮质上制备了一个2.5厘米的缺损。然后，成对股骨缺损中的一个用甲基丙烯酸甲酯填充，而另一个股骨不进行填充。然后对股骨进行轴向加载测试直至失效。在第二次测试中，成对的股骨以相同方式制备并进行扭矩测试直至失效。在第三次测试中，成对股骨中的一个制备了一个2.5厘米的缺损并用甲基丙烯酸甲酯填充，而另一个股骨保持完整。当将缺损用甲基丙烯酸甲酯填充的股骨与未处理的制备股骨进行比较时，发现轴向载荷强度显著增加约50%，扭矩强度增加约70%。似乎在内部固定时用甲基丙烯酸甲酯填充大的溶骨性缺损会显著增加轴向和扭转载荷的强度。
