Bertoni F, Calderoni P, Bacchini P, Campanacci M
J Bone Joint Surg Br. 1984 Mar;66(2):265-8. doi: 10.1302/0301-620X.66B2.6707066.
The clinical and pathological features of six cases of desmoplastic fibroma of bone are presented. Desmoplastic fibroma is rarely seen as a primary tumour of bone; when it does occur the sites of predilection are the long bones, but other sites such as the scapula and os calcis can be involved. Radiographically the lesion tends to expand the bone from within; it is well-demarcated and lytic, often with a trabeculated soap-bubble appearance. The cellular structure and the morphological arrangement are similar to those of aggressive fibromatosis of soft tissues. Differential diagnosis from malignant spindle-cell lesions of bone is important because the treatment of choice for desmoplastic fibroma of bone is simply excision with a thin layer of healthy tissue.
本文介绍了6例骨促结缔组织增生性纤维瘤的临床和病理特征。促结缔组织增生性纤维瘤作为原发性骨肿瘤较为罕见；当其发生时，好发部位为长骨，但其他部位如肩胛骨和跟骨也可受累。影像学上，病变倾向于从骨内部使骨膨胀；边界清晰，呈溶骨性，常呈小梁状肥皂泡样外观。其细胞结构和形态排列与软组织侵袭性纤维瘤病相似。与骨恶性梭形细胞病变进行鉴别诊断很重要，因为骨促结缔组织增生性纤维瘤的首选治疗方法是单纯切除并带有一层薄的健康组织。
