Beck K, Keener J P, Ricciardi P
J Math Biol. 1984;19(1):79-94. doi: 10.1007/BF00275932.
Mathematical models of a vector-borne infectious disease acting on a host population consisting of three genotypes which differ in susceptibility to, recovery from, and death due to the disease are presented and analyzed. Singular perturbation techniques are used to obtain a single differential equation describing the slow time evolution of gene frequencies.
