Munford P R, Tarlow G, Gerner R
J Nerv Ment Dis. 1984 Apr;172(4):228-31. doi: 10.1097/00005053-198404000-00007.
The interaction of imipramine and operant conditioning on weight gain in an anorexia nervosa patient was examined by a single-subject experiment consisting of a baseline and four treatment phases: phase 1--contingency management only; phase 2--contingency management plus imipramine; phase 3--contingency management plus imipramine placebo; phase 4--contingency management only. The results showed that the interaction of drug and behavior therapy had no significant effect on weight gain, but that imipramine may have contributed to a decrease in depression. Observations are made regarding weight changes related to passes and medication refusals.
通过一项单受试者实验，对一名神经性厌食症患者体重增加方面丙咪嗪与操作性条件反射的相互作用进行了研究。该实验包括一个基线期和四个治疗阶段：第一阶段——仅应急管理；第二阶段——应急管理加丙咪嗪；第三阶段——应急管理加丙咪嗪安慰剂；第四阶段——仅应急管理。结果表明，药物与行为疗法的相互作用对体重增加无显著影响，但丙咪嗪可能有助于减轻抑郁。对与外出和拒绝服药相关的体重变化进行了观察。
