Gileadi O, Lorberboum H, de Groot N, Hochberg A A
Mol Biol Rep. 1984 Jan;9(4):241-4. doi: 10.1007/BF00775355.
Free cytoplasmic mRNPs were isolated from human placenta. An activity of RNase was associated with these particles but was mostly inhibited by a labile protein inhibitor. Both RNase and RNase inhibitor were extractable from mRNPs by 0.5 M KCl. The nature of the association of the RNase-RNase inhibitor complex with mRNPs makes it suitable as a putative system for control of expression and turnover of mRNPs and therefore of protein synthesis.
从人胎盘中分离出游离的细胞质信使核糖核蛋白颗粒（mRNPs）。核糖核酸酶（RNase）的活性与这些颗粒相关，但大部分被一种不稳定的蛋白质抑制剂所抑制。RNase和RNase抑制剂都可以通过0.5M氯化钾从mRNPs中提取出来。RNase-RNase抑制剂复合物与mRNPs的结合性质使其适合作为一种推测的系统，用于控制mRNPs的表达和周转，从而控制蛋白质合成。
