小鼠趾长伸肌成熟移植物中肌纤维的大小。

The size of the myofibers in mature grafts of the mouse extensor digitorum longus muscle.

作者信息

Thomas D, Klueber K, Bourke D, Ontell M

出版信息

Muscle Nerve. 1984 Mar-Apr;7(3):226-31. doi: 10.1002/mus.880070307.

Abstract

The histochemical profile of stabilized orthotopically grafted mouse extensor digitorum longus muscles (EDL) and fiber type diameter distribution in the graft was compared with control muscles. Histochemical fiber typing, based on myofibrillar ATPase reactions, indicated that type 1 fiber accounted for less than 1%, type 2a fibers for 30%, and type 2b fibers for 69% of the total fiber population of the graft. In control muscles of 56-day-old and 156-day-old mice, type 1 fibers accounted for less than 1%, type 2a fibers for 36%, and type 2b fibers for 63% of the total fiber population of normal muscles. The regenerating myofibers in stabilized grafts failed to achieve the normal fiber diameter. The type 2b fibers exhibited greater growth inhibition than did type 2a fibers.

摘要

将稳定原位移植的小鼠趾长伸肌（EDL）的组织化学特征及移植肌中纤维类型的直径分布与对照肌肉进行了比较。基于肌原纤维ATP酶反应的组织化学纤维分型表明，移植肌中1型纤维占总纤维数的比例不到1%，2a型纤维占30%，2b型纤维占69%。在56日龄和156日龄小鼠的对照肌肉中，1型纤维占正常肌肉总纤维数的比例不到1%，2a型纤维占36%，2b型纤维占63%。稳定移植肌中再生的肌纤维未能达到正常的纤维直径。2b型纤维比2a型纤维表现出更大的生长抑制。