Gross B G
Plast Reconstr Surg. 1984 Apr;73(4):590-4. doi: 10.1097/00006534-198404000-00012.
Thirty-nine percent of 54 phenol face peel patients treated rapidly developed some form of cardiac arrhythmia. When half the face was treated on consecutive days, only 22 percent of 100 patients developed cardiac arrhythmias and these were less severe. Serum phenol levels varied from 4.4 to 337.1 mg/L. Neither age, sex, nor previous cardiac history were accurate predictors of cardiac arrhythmia susceptibility. There was no predictable relationship between serum phenol level and the appearance of cardiac arrhythmia. The duration of the cardiac arrhythmias (2 to 19 minutes) suggests that the risk of cardiac arrhythmia in phenol peeling can be reduced by dividing the face into several units and spacing the application of phenol to each unit 20 minutes apart.
54名接受苯酚面部脱皮治疗的患者中，39%迅速出现了某种形式的心律失常。当连续几天只治疗半张脸时，100名患者中只有22%出现心律失常，而且症状较轻。血清苯酚水平在4.4至337.1毫克/升之间。年龄、性别和既往心脏病史都不是心律失常易感性的准确预测指标。血清苯酚水平与心律失常的出现之间没有可预测的关系。心律失常的持续时间（2至19分钟）表明，通过将面部分成几个区域，并将苯酚涂抹在每个区域的时间间隔20分钟，可以降低苯酚脱皮时心律失常的风险。
