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颅骨软化是3个月大婴儿佝偻病的特征性体征吗?

Is craniotabes a pathognomonic sign of rickets in 3-month-old infants?

作者信息

Pettifor J M, Pentopoulos M, Moodley G P, Isdale J M, Ross F P

出版信息

S Afr Med J. 1984 Apr 7;65(14):549-51.

PMID:6710261
Abstract

Fifty-eight well Black infants between the ages of 10 and 15 weeks were examined for the presence of craniotabes and investigated for the presence of vitamin D deficiency and rickets. Thirty-five infants were found to have craniotabes and 5 of these had radiological evidence of rickets. No difference in dietary history, birth weight, weight gain, length or skull circumference was found between those with and those without craniotabes. Significantly more females than males had craniotabes. The majority of infants with craniotabes had normal biochemical values. Craniotabes is a common finding in 3-month-old infants and is of no help in diagnosing rickets in this age group.

摘要

对58名年龄在10至15周的健康黑人婴儿进行了颅骨软化检查,并对维生素D缺乏和佝偻病的情况进行了调查。发现35名婴儿有颅骨软化,其中5名有佝偻病的放射学证据。有颅骨软化和没有颅骨软化的婴儿在饮食史、出生体重、体重增加、身长或头围方面没有差异。患颅骨软化的女性明显多于男性。大多数有颅骨软化的婴儿生化指标正常。颅骨软化在3个月大的婴儿中很常见,对该年龄组佝偻病的诊断没有帮助。

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