Ichinose A, Mimuro J, Koide T, Aoki N
Thromb Res. 1984 Feb 15;33(4):401-7. doi: 10.1016/0049-3848(84)90079-3.
The plasma proteins alpha 2-plasmin inhibitor and histidine-rich glycoprotein were compared directly with respect to their effectiveness in inhibiting the binding of plasminogen to fibrin under the same experimental conditions. At their physiological concentrations, the presence of alpha 2-plasmin inhibitor more markedly decreased the binding of plasminogen to fibrin than histidine-rich glycoprotein. Significance of these findings in inhibition of fibrinolysis is discussed.
在相同实验条件下,直接比较了血浆蛋白α2-纤溶酶抑制剂和富含组氨酸糖蛋白在抑制纤溶酶原与纤维蛋白结合方面的有效性。在它们的生理浓度下,α2-纤溶酶抑制剂的存在比富含组氨酸糖蛋白更显著地降低了纤溶酶原与纤维蛋白的结合。讨论了这些发现对纤维蛋白溶解抑制的意义。