Thieke C, Nizze H
Z Gesamte Inn Med. 1984 Feb 1;39(3):37-40.
Among 237 patients who died of acute myocardial infarction (4% of the 5,390 autopsies from 1975 to 1979) 43 cases (18%) with a rupture of the cardiac wall were found. These 43 cases of rupture were compared with 43 non-rupture cases of the same period. In difference to the non-rupture cases the average weight of the heart was smaller. Myocardial scars, additional basic diseases and a lung oedema were rarer; an extended region of the infarction and an anamnestically known chronic ischemic heart disease were observed significantly more frequently. In what respect these and other analysed factors are responsible for the rupture mechanism, cannot be clearly estimated. Apart from a continuing hypertension as well as a relatively smaller weight of the heart and the absence of myocardial scars the extension of the area of the infarction as well as the possible effect of granulocytic enzymes in the area of the infarction appear significant for the origin of a heart rupture.
在237例死于急性心肌梗死的患者中（占1975年至1979年5390例尸检的4%），发现43例（18%）出现心脏壁破裂。将这43例破裂病例与同期43例未破裂病例进行比较。与未破裂病例不同，心脏的平均重量较小。心肌瘢痕、其他基础疾病和肺水肿较少见；梗死范围扩大和有既往已知慢性缺血性心脏病的情况明显更常见。这些以及其他分析因素在何种程度上导致破裂机制尚无法明确估计。除了持续性高血压、相对较小的心脏重量以及无心肌瘢痕外，梗死面积的扩大以及梗死区域粒细胞酶的可能作用似乎对心脏破裂的发生具有重要意义。
